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Adalat® Research

Adalat® (nifedipine GITS) is one of the most well-researched antihypertensive agents. Recent trials have focused on its effects beyond blood-pressure reduction:
INSIGHT was the first double-blind, prospective, randomised study to investigate the clinical outcome of treatment with Adalat® once-daily vs conventional treatment in hypertensive patients with additional cardiovascular risk factors.

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In addition to the main trial, INSIGHT side-arm studies and several additional INSIGHT subanalyses were performed, each of which have added to our understanding of the progression of cardiovascular disease in hypertensive patients.

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In ENCORE, the primary objectives were to assess the effects of treatment with Adalat® and/or cerivastatin on coronary endothelial dysfunction, coronary morphology and the progression of coronary atherosclerosis.

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The ACTION trial provides information on how blood-pressure control and additional effects of Adalat® translate into long-term clinical benefits. For further information on the results, please have a look at our ACTION website.

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